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Orai1 subunit stoichiometry of the mammalian CRAC channel pore

Agonist-activated Ca(2+) entry plays a critical role in Ca(2+) signalling in non-excitable cells. One mode of such entry is activated as a consequence of the depletion of intracellular Ca(2+) stores. This depletion is sensed by the protein STIM1 in the endoplasmic reticulum, which then translocates...

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Autors principals: Mignen, Olivier, Thompson, Jill L, Shuttleworth, Trevor J
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2375595/
https://ncbi.nlm.nih.gov/pubmed/18006576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2007.147249
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