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The molecular architecture of the arachidonate-regulated Ca(2+)-selective ARC channel is a pentameric assembly of Orai1 and Orai3 subunits

The activation of Ca(2+) entry is a critical component of agonist-induced cytosolic Ca(2+) signals in non-excitable cells. Although a variety of different channels may be involved in such entry, the recent identification of the STIM and Orai proteins has focused attention on the channels in which th...

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Détails bibliographiques
Auteurs principaux: Mignen, Olivier, Thompson, Jill L, Shuttleworth, Trevor J
Format: Artigo
Langue:Inglês
Publié: Blackwell Science Inc 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2754359/
https://ncbi.nlm.nih.gov/pubmed/19622606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2009.174193
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