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The molecular architecture of the arachidonate-regulated Ca(2+)-selective ARC channel is a pentameric assembly of Orai1 and Orai3 subunits
The activation of Ca(2+) entry is a critical component of agonist-induced cytosolic Ca(2+) signals in non-excitable cells. Although a variety of different channels may be involved in such entry, the recent identification of the STIM and Orai proteins has focused attention on the channels in which th...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Blackwell Science Inc
2009
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2754359/ https://ncbi.nlm.nih.gov/pubmed/19622606 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2009.174193 |
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