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Molecular basis of activation of the arachidonate-regulated Ca(2+) (ARC) channel, a store-independent Orai channel, by plasma membrane STIM1

Currently, Orai proteins are known to encode two distinct agonist-activated, highly calcium-selective channels: the store-operated Ca(2+) release-activated Ca(2+) (CRAC) channels, and the store-independent, arachidonic acid-activated ARC channels. Surprisingly, whilst the trigger for activation of t...

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Detalhes bibliográficos
Main Authors: Thompson, Jill L, Shuttleworth, Trevor J
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3731610/
https://ncbi.nlm.nih.gov/pubmed/23690558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2013.256784
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