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Grassystatins D–F, Potent Aspartic Protease Inhibitors from Marine Cyanobacteria as Potential Antimetastatic Agents Targeting Invasive Breast Cancer

Three new modified peptides named grassystatins D–F (1–3) were discovered from a marine cyanobacterium from Guam. Their structures were elucidated using NMR spectroscopy and mass spectrometry (MS). The hallmark structural feature in the peptides is a statine unit which contributes to their aspartic...

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Detalhes bibliográficos
Publicado no:J Nat Prod
Main Authors: Al-Awadhi, Fatma H., Law, Brian K., Paul, Valerie J., Luesch, Hendrik
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5764543/
https://ncbi.nlm.nih.gov/pubmed/29087712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jnatprod.7b00551
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