Histone deacetylase 2 (HDAC2) attenuates lipopolysaccharide (LPS)-induced inflammation by regulating PAI-1 expression

BACKGROUND: Sepsis is a life-threatening organ dysfunction caused by dysregulated host response to infection, and is primarily characterized by an uncontrolled systemic inflammatory response. In the present study, we developed an effective adjunct therapy mediated by a novel mechanism, to attenuate...

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Detalles Bibliográficos
Publicado en:J Inflamm (Lond)
Main Authors: Fang, Wen-Feng, Chen, Yu-Mu, Lin, Chiung-Yu, Huang, Hui-Lin, Yeh, Hua, Chang, Ya-Ting, Huang, Kuo-Tung, Lin, Meng-Chih
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2018
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Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5763578/
https://ncbi.nlm.nih.gov/pubmed/29344006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12950-018-0179-6
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