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Single‐Center Evaluation of the Pharmacokinetics and Safety of the Angiotensin II Receptor Antagonist Azilsartan Medoxomil in Mild to Moderate Hepatic Impairment

Azilsartan medoxomil (AZL‐M) is a potent angiotensin II receptor blocker that decreases blood pressure in a dose‐dependent manner. It is a prodrug that is not detected in blood after its oral administration because of its rapid hydrolysis to the active moiety, azilsartan (AZL). AZL undergoes further...

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Detalhes bibliográficos
Publicado no:J Clin Pharmacol
Main Authors: Dudkowski, Caroline, Karim, Aziz, Zhao, Zhen, Alonso, Alberto B., Garg, Dyal, Preston, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5763333/
https://ncbi.nlm.nih.gov/pubmed/28750149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcph.970
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