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Effects of Age, Sex, and Race on the Safety and Pharmacokinetics of Single and Multiple Doses of Azilsartan Medoxomil in Healthy Subjects

BACKGROUND AND OBJECTIVE: Azilsartan medoxomil (AZL-M) is an angiotensin II receptor blocker approved to treat hypertension. After oral dosing, AZL-M is quickly hydrolyzed to azilsartan (AZL). The aims of this study were to assess the effects of age, sex, and race on the pharmacokinetics of AZL-M in...

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Publicado en:Clin Pharmacokinet
Main Authors: Harrell, Robert E., Karim, Aziz, Zhang, Wencan, Dudkowski, Caroline
Formato: Artigo
Idioma:Inglês
Publicado: Springer International Publishing 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4823318/
https://ncbi.nlm.nih.gov/pubmed/26507722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-015-0333-8
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