Single-dose pharmacokinetics and safety of azilsartan medoxomil in children and adolescents with hypertension as compared to healthy adults

PURPOSE: This open-label, multicenter, single-dose study characterized the pharmacokinetics and short-term safety of azilsartan medoxomil (AZL-M) in hypertensive pediatric subjects (12–16 years [cohort 1a; n = 9]; 6–11 years [cohort 2; n = 8]; 4–5 years [cohort 3; n = 3]). METHODS: Model-based simul...

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Detaylı Bibliyografya
Yayımlandı:Eur J Clin Pharmacol
Asıl Yazarlar: Webb, Nicholas J. A., Wells, Thomas, Tsai, Max, Zhao, Zhen, Juhasz, Attila, Dudkowski, Caroline
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Springer Berlin Heidelberg 2016
Konular:
Pharmacokinetics and Disposition
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4792355/
https://ncbi.nlm.nih.gov/pubmed/26725367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00228-015-1987-8
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