Validation of a Next-Generation Sequencing Assay for Clinical Molecular Oncology

Currently, oncology testing includes molecular studies and cytogenetic analysis to detect genetic aberrations of clinical significance. Next-generation sequencing (NGS) allows rapid analysis of multiple genes for clinically actionable somatic variants. The WUCaMP assay uses targeted capture for NGS...

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Pubblicato in:J Mol Diagn
Autori principali: Cottrell, Catherine E., Al-Kateb, Hussam, Bredemeyer, Andrew J., Duncavage, Eric J., Spencer, David H., Abel, Haley J., Lockwood, Christina M., Hagemann, Ian S., O’Guin, Stephanie M., Burcea, Lauren C., Sawyer, Christopher S., Oschwald, Dayna M., Stratman, Jennifer L., Sher, Dorie A., Johnson, Mark R., Brown, Justin T., Cliften, Paul F., George, Bijoy, McIntosh, Leslie D., Shrivastava, Savita, Nguyen, TuDung T., Payton, Jacqueline E., Watson, Mark A., Crosby, Seth D., Head, Richard D., Mitra, Robi D., Nagarajan, Rakesh, Kulkarni, Shashikant, Seibert, Karen, Virgin, Herbert W., Milbrandt, Jeffrey, Pfeifer, John D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Investigative Pathology 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762937/
https://ncbi.nlm.nih.gov/pubmed/24211365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmoldx.2013.10.002
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