PAXX and Xlf interplay revealed by impaired CNS development and immunodeficiency of double KO mice

The repair of DNA double-stranded breaks (DNAdsb) through non-homologous end joining (NHEJ) is a prerequisite for the proper development of the central nervous system and the adaptive immune system. Yet, mice with Xlf or PAXX loss of function are viable and present with very mild immune phenotypes,...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Abramowski, Vincent, Etienne, Olivier, Elsaid, Ramy, Yang, Junjie, Berland, Aurélie, Kermasson, Laetitia, Roch, Benoit, Musilli, Stefania, Moussu, Jean-Paul, Lipson-Ruffert, Karelia, Revy, Patrick, Cumano, Ana, Boussin, François D, de Villartay, Jean-Pierre
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2018
Assuntos:
Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762856/
https://ncbi.nlm.nih.gov/pubmed/29077092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2017.184
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados