N6-isopentenyladenosine dual targeting of AMPK and Rab7 prenylation inhibits melanoma growth through the impairment of autophagic flux

Targeting the autophagic process is considered a promising therapeutic strategy in cancer since a great number of tumors, including melanoma, show high basal levels of protective autophagy that contributes to tumor progression and chemoresistance. Here, exploiting both in vitro and in vivo approache...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Cell Death Differ
Main Authors: Ranieri, Roberta, Ciaglia, Elena, Amodio, Giuseppina, Picardi, Paola, Proto, Maria Chiara, Gazzerro, Patrizia, Laezza, Chiara, Remondelli, Paolo, Bifulco, Maurizio, Pisanti, Simona
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2018
Fag:
Original Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762849/
https://ncbi.nlm.nih.gov/pubmed/29027991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2017.165
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker