Coordinated repression of BIM and PUMA by Epstein–Barr virus latent genes maintains the survival of Burkitt lymphoma cells

While the association of Epstein–Barr virus (EBV) with Burkitt lymphoma (BL) has long been recognised, the precise role of the virus in BL pathogenesis is not fully resolved. EBV can be lost spontaneously from some BL cell lines, and these EBV-loss lymphoma cells reportedly have a survival disadvant...

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Publicat a:Cell Death Differ
Autors principals: Fitzsimmons, Leah, Boyce, Andrew J, Wei, Wenbin, Chang, Catherine, Croom-Carter, Deborah, Tierney, Rosemary J, Herold, Marco J, Bell, Andrew I, Strasser, Andreas, Kelly, Gemma L, Rowe, Martin
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2018
Matèries:
Original Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762840/
https://ncbi.nlm.nih.gov/pubmed/28960205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2017.150
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