Coordinated repression of BIM and PUMA by Epstein–Barr virus latent genes maintains the survival of Burkitt lymphoma cells

While the association of Epstein–Barr virus (EBV) with Burkitt lymphoma (BL) has long been recognised, the precise role of the virus in BL pathogenesis is not fully resolved. EBV can be lost spontaneously from some BL cell lines, and these EBV-loss lymphoma cells reportedly have a survival disadvant...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Fitzsimmons, Leah, Boyce, Andrew J, Wei, Wenbin, Chang, Catherine, Croom-Carter, Deborah, Tierney, Rosemary J, Herold, Marco J, Bell, Andrew I, Strasser, Andreas, Kelly, Gemma L, Rowe, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2018
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762840/
https://ncbi.nlm.nih.gov/pubmed/28960205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2017.150
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