Coordinated repression of BIM and PUMA by Epstein–Barr virus latent genes maintains the survival of Burkitt lymphoma cells

While the association of Epstein–Barr virus (EBV) with Burkitt lymphoma (BL) has long been recognised, the precise role of the virus in BL pathogenesis is not fully resolved. EBV can be lost spontaneously from some BL cell lines, and these EBV-loss lymphoma cells reportedly have a survival disadvant...

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Bibliographische Detailangaben
Veröffentlicht in:Cell Death Differ
Hauptverfasser: Fitzsimmons, Leah, Boyce, Andrew J, Wei, Wenbin, Chang, Catherine, Croom-Carter, Deborah, Tierney, Rosemary J, Herold, Marco J, Bell, Andrew I, Strasser, Andreas, Kelly, Gemma L, Rowe, Martin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2018
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Original Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762840/
https://ncbi.nlm.nih.gov/pubmed/28960205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2017.150
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