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Blimp-1/PRDM1 is a critical regulator of Type III Interferon responses in mammary epithelial cells

The transcriptional repressor Blimp-1 originally cloned as a silencer of type I interferon (IFN)-β gene expression controls cell fate decisions in multiple tissue contexts. Conditional inactivation in the mammary gland was recently shown to disrupt epithelial cell architecture. Here we report that B...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Elias, Salah, Robertson, Elizabeth J., Bikoff, Elizabeth K., Mould, Arne W.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762727/
https://ncbi.nlm.nih.gov/pubmed/29321612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-18652-9
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