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Blimp1/Prdm1 governs terminal differentiation of endovascular trophoblast giant cells and defines multipotent progenitors in the developing placenta

Developmental arrest of Blimp1/Prdm1 mutant embryos at around embryonic day 10.5 (E10.5) has been attributed to placental disturbances. Here we investigate Blimp1/Prdm1 requirements in the trophoblast cell lineage. Loss of function disrupts specification of the invasive spiral artery-associated trop...

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Main Authors: Mould, Arne, Morgan, Marc A.J., Li, Li, Bikoff, Elizabeth K., Robertson, Elizabeth J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Cold Spring Harbor Laboratory Press 2012
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3444732/
https://ncbi.nlm.nih.gov/pubmed/22987638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.199828.112
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