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Alternative Splicing Regulates Prdm1/Blimp-1 DNA Binding Activities and Corepressor Interactions

Prdm1/Blimp-1 is a master regulator of gene expression in diverse tissues of the developing embryo and adult organism. Its C-terminal zinc finger domain mediates nuclear import, DNA binding, and recruitment of the corepressors G9a and HDAC1/2. Alternatively spliced transcripts lacking exon 7 sequenc...

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Detalhes bibliográficos
Main Authors: Morgan, Marc A. J., Mould, Arne W., Li, Li, Robertson, Elizabeth J., Bikoff, Elizabeth K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3422002/
https://ncbi.nlm.nih.gov/pubmed/22733990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00174-12
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