Actein induces autophagy and apoptosis in human bladder cancer by potentiating ROS/JNK and inhibiting AKT pathways

Human bladder cancer is a common genitourinary malignant cancer worldwide. However, new therapeutic strategies are required to overcome its stagnated survival rate. Triterpene glycoside Actein (ACT), extracted from the herb black cohosh, suppresses the growth of human breast cancer cells. Our study...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Ji, Lu, Zhong, Bing, Jiang, Xi, Mao, Fei, Liu, Gang, Song, Bin, Wang, Cheng-Yuan, Jiao, Yong, Wang, Jiang-Ping, Xu, Zhi-Bin, Li, Xing, Zhan, Bo
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762528/
https://ncbi.nlm.nih.gov/pubmed/29348843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22274
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