Actein induces autophagy and apoptosis in human bladder cancer by potentiating ROS/JNK and inhibiting AKT pathways

Human bladder cancer is a common genitourinary malignant cancer worldwide. However, new therapeutic strategies are required to overcome its stagnated survival rate. Triterpene glycoside Actein (ACT), extracted from the herb black cohosh, suppresses the growth of human breast cancer cells. Our study...

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Библиографические подробности
Опубликовано в: :Oncotarget
Главные авторы: Ji, Lu, Zhong, Bing, Jiang, Xi, Mao, Fei, Liu, Gang, Song, Bin, Wang, Cheng-Yuan, Jiao, Yong, Wang, Jiang-Ping, Xu, Zhi-Bin, Li, Xing, Zhan, Bo
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals LLC 2017
Предметы:
Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762528/
https://ncbi.nlm.nih.gov/pubmed/29348843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22274
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