ROS activates JNK-mediated autophagy to counteract apoptosis in mouse mesenchymal stem cells in vitro

AIM: Transplantation of mesenchymal stem cells (MSCs) for the treatment of diabetic erectile dysfunction (ED) is hampered by apoptosis of the transplanted cells. In diabetic ED, there is increased oxidative stress and decreased NO in the corpora cavernosa, and reactive oxygen species (ROS) induce ap...

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Detalhes bibliográficos
Publicado no:Acta Pharmacol Sin
Main Authors: Liu, Guan-yu, Jiang, Xiao-xue, Zhu, Xin, He, Wei-yang, Kuang, You-lin, Ren, Ke, Lin, Yong, Gou, Xin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816227/
https://ncbi.nlm.nih.gov/pubmed/26592514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2015.101
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