Adipose Tissue is Enriched for Activated and Late-differentiated CD8+ T cells, and Shows Distinct CD8+ Receptor Usage, Compared to Blood in HIV-infected Persons

BACKGROUND: Adverse viral and medication effects on adipose tissue contribute to the development of metabolic disease in HIV-infected persons, but T cells also have a central role modulating local inflammation and adipocyte function. We sought to characterize potentially pro-inflammatory T cell popu...

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Détails bibliographiques
Publié dans:J Acquir Immune Defic Syndr
Auteurs principaux: Koethe, John R., McDonnell, Wyatt, Kennedy, Arion, Abana, Chike O., Pilkinton, Mark, Setliff, Ian, Georgiev, Ivelin, Barnett, Louise, Hager, Cindy C., Smith, Rita, Kalams, Spyros A., Hasty, Alyssa, Mallal, Simon
Format: Artigo
Langue:Inglês
Publié: 2018
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762435/
https://ncbi.nlm.nih.gov/pubmed/29040163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0000000000001573
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