Mechanisms by which a very low calorie diet reverses hyperglycemia in a rat model of type 2 diabetes

Caloric restriction rapidly reverses type 2 diabetes (T2D) but the mechanism(s) of this reversal are poorly understood. Here we show that three days of a very low-calorie diet (VLCD, 1/4 their typical intake) lowered plasma glucose and insulin concentrations in a rat model of T2D without altering bo...

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Bibliografske podrobnosti
izdano v:Cell Metab
Main Authors: Perry, Rachel J., Peng, Liang, Cline, Gary W., Wang, Yongliang, Rabin-Court, Aviva, Song, Joongyu D., Zhang, Dongyan, Zhang, Xian-Man, Nozaki, Yuichi, Dufour, Sylvie, Petersen, Kitt Falk, Shulman, Gerald I.
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762419/
https://ncbi.nlm.nih.gov/pubmed/29129786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2017.10.004
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