Anti-neoplastic drugs increase caveolin-1-dependent migration, invasion and metastasis of cancer cells

Expression of the scaffolding protein Caveolin-1 (CAV1) enhances migration and invasion of metastatic cancer cells. Yet, CAV1 also functions as a tumor suppressor in early stages of cancer, where expression is suppressed by epigenetic mechanisms. Thus, we sought to identify stimuli/mechanisms that r...

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Detalles Bibliográficos
Publicado en:Oncotarget
Main Authors: Díaz-Valdivia, Natalia I., Calderón, Claudia C., Díaz, Jorge E., Lobos-González, Lorena, Sepulveda, Hugo, Ortíz, Rina J., Martinez, Samuel, Silva, Veronica, Maldonado, Horacio J., Silva, Patricio, Wehinger, Sergio, Burzio, Verónica A., Torres, Vicente A., Montecino, Martín, Leyton, Lisette, Quest, Andrew F.G.
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2017
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762371/
https://ncbi.nlm.nih.gov/pubmed/29340103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22955
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