CRISPR-Cas9 HDR system enhances AQP1 gene expression

Ionizing radiation (IR) isthe primarytherapeutic tool to treat patients with cancerous lesions located in the head and neck. In many patients, IR results in irreversible and severe salivary gland dysfunction or xerostomia. Currently there are no effective treatment options to reduce the effects of x...

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Detalhes bibliográficos
Publicado no:Oncotarget
Principais autores: Wang, Zhimin, Wang, Yaohe, Wang, Songling, Zhang, Li-Rong, Zhang, Na, Cheng, Zhenguo, Liu, Qingshi, Shields, Kelly J., Hu, Baoli, Passineau, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762352/
https://ncbi.nlm.nih.gov/pubmed/29340084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22901
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