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Efficiently Editing the Vaccinia Virus Genome by Using the CRISPR-Cas9 System
Vaccinia virus (VACV) continues to be used in immunotherapy for the prevention of infectious diseases and treatment of cancer since its use for the eradication of smallpox. However, the current method of editing the VACV genome is not efficient. Here, we demonstrate that the CRISPR-Cas9 system can b...
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| Publicado no: | J Virol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4403460/ https://ncbi.nlm.nih.gov/pubmed/25741005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00339-15 |
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