CRISPR-Cas9 HDR system enhances AQP1 gene expression

Ionizing radiation (IR) isthe primarytherapeutic tool to treat patients with cancerous lesions located in the head and neck. In many patients, IR results in irreversible and severe salivary gland dysfunction or xerostomia. Currently there are no effective treatment options to reduce the effects of x...

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Publicado en:Oncotarget
Autores principales: Wang, Zhimin, Wang, Yaohe, Wang, Songling, Zhang, Li-Rong, Zhang, Na, Cheng, Zhenguo, Liu, Qingshi, Shields, Kelly J., Hu, Baoli, Passineau, Michael J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762352/
https://ncbi.nlm.nih.gov/pubmed/29340084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22901
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