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CRISPR-Cas9 HDR system enhances AQP1 gene expression

Ionizing radiation (IR) isthe primarytherapeutic tool to treat patients with cancerous lesions located in the head and neck. In many patients, IR results in irreversible and severe salivary gland dysfunction or xerostomia. Currently there are no effective treatment options to reduce the effects of x...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Wang, Zhimin, Wang, Yaohe, Wang, Songling, Zhang, Li-Rong, Zhang, Na, Cheng, Zhenguo, Liu, Qingshi, Shields, Kelly J., Hu, Baoli, Passineau, Michael J.
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762352/
https://ncbi.nlm.nih.gov/pubmed/29340084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22901
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