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CRISPR-Cas9 HDR system enhances AQP1 gene expression

Ionizing radiation (IR) isthe primarytherapeutic tool to treat patients with cancerous lesions located in the head and neck. In many patients, IR results in irreversible and severe salivary gland dysfunction or xerostomia. Currently there are no effective treatment options to reduce the effects of x...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Wang, Zhimin, Wang, Yaohe, Wang, Songling, Zhang, Li-Rong, Zhang, Na, Cheng, Zhenguo, Liu, Qingshi, Shields, Kelly J., Hu, Baoli, Passineau, Michael J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762352/
https://ncbi.nlm.nih.gov/pubmed/29340084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22901
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