Inhibition of polo-like kinase 4 (PLK4): a new therapeutic option for rhabdoid tumors and pediatric medulloblastoma

Rhabdoid tumors (RT) are highly aggressive and vastly unresponsive embryonal tumors. They are the most common malignant CNS tumors in infants below 6 months of age. Medulloblastomas (MB) are embryonal tumors that arise in the cerebellum and are the most frequent pediatric malignant brain tumors. Des...

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Detalles Bibliográficos
Publicado en:Oncotarget
Main Authors: Sredni, Simone Treiger, Bailey, Anders W., Suri, Amreena, Hashizume, Rintaro, He, Xingyao, Louis, Nundia, Gokirmak, Tufan, Piper, David R., Watterson, Daniel M., Tomita, Tadanori
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2017
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762315/
https://ncbi.nlm.nih.gov/pubmed/29340047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22704
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