Altered GNAS imprinting due to folic acid deficiency contributes to poor embryo development and may lead to neural tube defects

Disturbed epigenetic modifications have been linked to the pathogenesis of Neural Tube Defects (NTDs) in those with folate deficiency during pregnancy. However, evidence is lacking to delineate the critical region in epigenome regulated by parental folic acid and mechanisms by which folate deficienc...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Wang, Li, Chang, Shaoyan, Wang, Zhen, Wang, Shan, Huo, Junsheng, Ding, Gangqiang, Li, Rui, Liu, Chi, Shangguan, Shaofang, Lu, Xiaolin, Zhang, Ting, Qiu, Zhiyong, Wu, Jianxin
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762285/
https://ncbi.nlm.nih.gov/pubmed/29340017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22731
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