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Folate deficiency disturbs hsa‐let‐7 g level through methylation regulation in neural tube defects

Folic acid deficiency during pregnancy is believed to be a high‐risk factor for neural tube defects (NTDs). Disturbed epigenetic modifications, including miRNA regulation, have been linked to the pathogenesis of NTDs in those with folate deficiency. However, the mechanism by which folic acid‐regulat...

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Библиографические подробности
Опубликовано в: :J Cell Mol Med
Главные авторы: Wang, Li, Shangguan, Shaofang, Xin, Yu, Chang, Shaoyan, Wang, Zhen, Lu, Xiaolin, Wu, Lihua, Niu, Bo, Zhang, Ting
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5706510/
https://ncbi.nlm.nih.gov/pubmed/28631291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13228
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