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Folate deficiency disturbs hsa‐let‐7 g level through methylation regulation in neural tube defects

Folic acid deficiency during pregnancy is believed to be a high‐risk factor for neural tube defects (NTDs). Disturbed epigenetic modifications, including miRNA regulation, have been linked to the pathogenesis of NTDs in those with folate deficiency. However, the mechanism by which folic acid‐regulat...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Wang, Li, Shangguan, Shaofang, Xin, Yu, Chang, Shaoyan, Wang, Zhen, Lu, Xiaolin, Wu, Lihua, Niu, Bo, Zhang, Ting
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5706510/
https://ncbi.nlm.nih.gov/pubmed/28631291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13228
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