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Quantification of tolvaptan in rabbit plasma by LC–MS/MS: Application to a pharmacokinetic study()
A sensitive, selective and high-throughput liquid chromatography–tandem mass spectrometry (LC–ESI–MS/MS) method was developed and validated for the quantitation of tolvaptan in rabbit plasma. Sample clean-up involved liquid–liquid extraction (LLE) and chromatography was performed on Zorbax SB C(18)...
Gardado en:
| Publicado en: | J Pharm Anal |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Xi'an Jiaotong University
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5762243/ https://ncbi.nlm.nih.gov/pubmed/29403951 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpha.2014.09.001 |
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