Simultaneous Quantification of Baricitinib and Methotrexate in Rat Plasma by LC-MS/MS: Application to a Pharmacokinetic Study

Efficacy assessments using a combination of baricitinib and methotrexate necessitate the development of an analytical method for the determination of both drugs in plasma with precision. A high-performance liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was developed for the simulta...

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Publicat a:Sci Pharm
Autors principals: Veeraraghavan, Sridhar, Thappali, Satheeshmanikandan R. S., Viswanadha, Srikant, Vakkalanka, Swaroop, Rangaswamy, Manivannan
Format: Artigo
Idioma:Inglês
Publicat: The Austrian Journal of Pharmaceutical Sciences 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4871186/
https://ncbi.nlm.nih.gov/pubmed/27222609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3797/scipharm.1510-08
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