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Simultaneous quantification of lidocaine and prilocaine in human plasma by LC-MS/MS and its application in a human pharmacokinetic study

OBJECTIVE: The aim of the work was to develop and validate a simple, sensitive and selective Liquid chromatography with Mass spectroscopic method for simultaneous quantification of lidocaine and prilocaine in human plasma. DESIGN AND METHODS: Analytes and the internal standards from human plasma wer...

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Detalhes bibliográficos
Publicado no:Pract Lab Med
Main Authors: Rao Yadlapalli, Siva Sankara, Katari, Naresh Kumar, Manabolu Surya, Surendra Babu, Karra, Vijaya Kumari, Kommineni, Vinutha, Jonnalagadda, Sreekantha B.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6687230/
https://ncbi.nlm.nih.gov/pubmed/31414038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.plabm.2019.e00129
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