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Simultaneous determination of losartan, losartan acid and amlodipine in human plasma by LC-MS/MS and its application to a human pharmacokinetic study

INTRODUCTION: A simple, rapid and sensitive liquid chromatography-tandem mass spectrometric assay method has been developed and fully validated for simultaneous quantification of losartan and its active metabolite, losartan carboxylic acid, and amlodipine in human plasma. Irbesartan was used as an i...

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Bibliografiska uppgifter
Huvudupphovsmän: Karra, Vijaya Kumari, Pilli, Nageswara Rao, Inamadugu, Jaswanth Kumar, Rao, J. V. L. N. Seshagiri
Materialtyp: Artigo
Språk:Inglês
Publicerad: Medknow Publications & Media Pvt Ltd 2012
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3658069/
https://ncbi.nlm.nih.gov/pubmed/23781473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/2229-4708.97711
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