Simultaneous Determination of Celecoxib, Erlotinib, and its Metabolite Desmethyl-Erlotinib (OSI-420) in Rat Plasma by Liquid chromatography/Tandem Mass Spectrometry with Positive/Negative Ion-Switching Electrospray Ionisation

A new method for the simultaneous determination of celecoxib, erlotinib, and its active metabolite desmethyl-erlotinib (OSI-420) in rat plasma, by liquid chromatography/tandem mass spectrometry with positive/negative ion-switching electrospray ionization mode, was developed and validated. Protein pr...

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Hlavní autoři: Thappali, Satheeshmanikandan R. S., Varanasi, Kanthikiran, Veeraraghavan, Sridhar, Arla, Rambabu, Chennupati, Sandhya, Rajamanickam, Madheswaran, Vakkalanka, Swaroop, Khagga, Mukkanti
Médium: Artigo
Jazyk:Inglês
Vydáno: Österreichische Apotheker-Verlagsgesellschaft 2012
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3447620/
https://ncbi.nlm.nih.gov/pubmed/23008811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3797/scipharm.1205-09
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