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Disposition of Erlotinib and Its Metabolite OSI420 in a Patient with High Bilirubin Levels
Erlotinib is an oral epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor approved for the treatment of non-small cell lung cancer and when combined with gemcitabine for pancreatic cancer. Dose reduction of erlotinib in patients with severe hepatic impairment has been established. We pr...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
S. Karger AG
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3901587/ https://ncbi.nlm.nih.gov/pubmed/24474924 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000357211 |
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