Systemic multilineage engraftment in mice after in utero transplantation with human hematopoietic stem cells

IUHCT of human cord blood–derived CD34(+) cells into fetal NSG mice results in systemic multilineage engraftment with human cells. Preconditioning with in utero injection of an anti-c-Kit receptor antibody (ACK2) results in an improved rate of engraftment.

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Witt, Russell G., Kreger, Emily M., Buckman, Laura B., Moradi, Patriss W., Ho, Phong T., Derderian, S. Christopher, Tsai, Perry, Baker, Chris, Schramm, Nathaniel, Cleary, Rachel, Garcia, J. Victor, MacKenzie, Tippi C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2018
Assuntos:
Stimulus Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5761626/
https://ncbi.nlm.nih.gov/pubmed/29344586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017011585
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