In utero depletion of fetal hematopoietic stem cells improves engraftment after neonatal transplantation in mice

Although in utero hematopoietic cell transplantation is a promising strategy to treat congenital hematopoietic disorders, levels of engraftment have not been therapeutic for diseases in which donor cells have no survival advantage. We used an antibody against the murine c-Kit receptor (ACK2) to depl...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Derderian, S. Christopher, Togarrati, P. Priya, King, Charmin, Moradi, Patriss W., Reynaud, Damien, Czechowicz, Agnieszka, Weissman, Irving L., MacKenzie, Tippi C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society of Hematology 2014
Pynciau:
Transplantation
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4126335/
https://ncbi.nlm.nih.gov/pubmed/24879814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-02-550327
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