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Direct and indirect antigen presentation lead to deletion of donor-specific T cells after in utero hematopoietic cell transplantation in mice

In utero hematopoietic cell transplantation (IUHCTx) is a promising method to induce donor-specific tolerance but the mechanisms of antigen presentation that educate host T cells and the relative importance of deletion vs regulation in this setting are unknown. We studied the roles of direct and ind...

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Hlavní autoři: Nijagal, Amar, Derderian, Chris, Le, Tom, Jarvis, Erin, Nguyen, Linda, Tang, Qizhi, MacKenzie, Tippi C.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668492/
https://ncbi.nlm.nih.gov/pubmed/23610372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-10-463174
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