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Amyloid-β Contributes to Blood–Brain Barrier Leakage in Transgenic Human Amyloid Precursor Protein Mice and in Humans With Cerebral Amyloid Angiopathy

BACKGROUND AND PURPOSE: Cerebral amyloid angiopathy (CAA) is a degenerative disorder characterized by amyloid-β (Aβ) deposition in the blood–brain barrier (BBB). CAA contributes to injuries of the neurovasculature including lobar hemorrhages, cortical microbleeds, ischemia, and superficial hemosider...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Stroke
Prif Awduron: Hartz, Anika M.S., Bauer, Björn, Soldner, Emma L.B., Wolf, Andrea, Boy, Sandra, Backhaus, Roland, Mihaljevic, Ivan, Bogdahn, Ulrich, Klünemann, Hans H., Schuierer, Gerhard, Schlachetzki, Felix
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5761312/
https://ncbi.nlm.nih.gov/pubmed/22116809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.111.627562
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