A carregar...

Restoring Blood-Brain Barrier P-Glycoprotein Reduces Brain Amyloid-β in a Mouse Model of Alzheimer's Disease

Reduced clearance of amyloid-β (Aβ) from brain partly underlies increased Aβ brain accumulation in Alzheimer's disease (AD). The mechanistic basis for this pathology is unknown, but recent evidence suggests a neurovascular component in AD etiology. We show here that the ATP-driven pump, P-glyco...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Hartz, Anika M. S., Miller, David S., Bauer, Björn
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872973/
https://ncbi.nlm.nih.gov/pubmed/20101004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.109.061754
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!