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17-β-Estradiol: a powerful modulator of blood–brain barrier BCRP activity

The ATP-driven efflux transporter, breast cancer resistance protein (BCRP), handles many therapeutic drugs, including chemotherapeutics, limiting their ability to cross the blood–brain barrier. This study provides new insight into rapid, nongenomic regulation of BCRP transport activity at the blood–...

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Autors principals: Hartz, Anika M S, Mahringer, Anne, Miller, David S, Bauer, Björn
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023406/
https://ncbi.nlm.nih.gov/pubmed/20216549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2010.36
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