17-β-Estradiol: a powerful modulator of blood–brain barrier BCRP activity

The ATP-driven efflux transporter, breast cancer resistance protein (BCRP), handles many therapeutic drugs, including chemotherapeutics, limiting their ability to cross the blood–brain barrier. This study provides new insight into rapid, nongenomic regulation of BCRP transport activity at the blood–...

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Main Authors: Hartz, Anika M S, Mahringer, Anne, Miller, David S, Bauer, Björn
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2010
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023406/
https://ncbi.nlm.nih.gov/pubmed/20216549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2010.36
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