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17-β-Estradiol: a powerful modulator of blood–brain barrier BCRP activity

The ATP-driven efflux transporter, breast cancer resistance protein (BCRP), handles many therapeutic drugs, including chemotherapeutics, limiting their ability to cross the blood–brain barrier. This study provides new insight into rapid, nongenomic regulation of BCRP transport activity at the blood–...

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Detalhes bibliográficos
Main Authors: Hartz, Anika M S, Mahringer, Anne, Miller, David S, Bauer, Björn
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023406/
https://ncbi.nlm.nih.gov/pubmed/20216549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2010.36
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