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The eIF2-alpha kinase HRI: a potential target beyond the red blood cell
INTRODUCTION: The eIF2α kinase heme-regulated inhibitor (HRI) is one of four well-described kinases that phosphorylate eIF2α in response to various cell stressors, resulting in reduced ternary complex formation and attenuation of mRNA translation. Although HRI is well known for its role as a heme se...
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| Publicado no: | Expert Opin Ther Targets |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5761058/ https://ncbi.nlm.nih.gov/pubmed/29063813 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14728222.2017.1397133 |
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