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Activatable iRGD-based peptide monolith: targeting, internalization, and fluorescence activation for precise tumor imaging
A disulfide-bridged cyclic RGD peptide, named iRGD (internalizing RGD, c(CRGDK/RGPD/EC)), is known to facilitate tumor targeting as well as tissue penetration. After the RGD motif-induced targeting on αv integrins expressed near tumor tissue, iRGD encounters proteolytic cleavage to expose the CendR...
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Publicado no: | J Control Release |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5759763/ https://ncbi.nlm.nih.gov/pubmed/27349354 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2016.06.032 |
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