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Mechanism of formation of a toroid around DNA by the mismatch sensor protein

The DNA mismatch repair (MMR) pathway removes errors that appear during genome replication. MutS is the primary mismatch sensor and forms an asymmetric dimer that encircles DNA to bend it to scan for mismatches. The mechanism utilized to load DNA into the central tunnel was unknown and the origin of...

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Detaylı Bibliyografya
Yayımlandı:Nucleic Acids Res
Asıl Yazarlar: Nirwal, Shivlee, Kulkarni, Dhananjaya S, Sharma, Amit, Rao, Desirazu N, Nair, Deepak T
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5758902/
https://ncbi.nlm.nih.gov/pubmed/29182773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx1149
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