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Mechanism of formation of a toroid around DNA by the mismatch sensor protein
The DNA mismatch repair (MMR) pathway removes errors that appear during genome replication. MutS is the primary mismatch sensor and forms an asymmetric dimer that encircles DNA to bend it to scan for mismatches. The mechanism utilized to load DNA into the central tunnel was unknown and the origin of...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5758902/ https://ncbi.nlm.nih.gov/pubmed/29182773 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx1149 |
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