A Thermus phage protein inhibits host RNA polymerase by preventing template DNA strand loading during open promoter complex formation

RNA polymerase (RNAP) is a major target of gene regulation. Thermus thermophilus bacteriophage P23–45 encodes two RNAP binding proteins, gp39 and gp76, which shut off host gene transcription while allowing orderly transcription of phage genes. We previously reported the structure of the T. thermophi...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nucleic Acids Res
Egile Nagusiak: Ooi, Wei-Yang, Murayama, Yuko, Mekler, Vladimir, Minakhin, Leonid, Severinov, Konstantin, Yokoyama, Shigeyuki, Sekine, Shun-ichi
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2018
Gaiak:
Structural Biology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5758890/
https://ncbi.nlm.nih.gov/pubmed/29165680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx1162
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