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Crystallization and preliminary X-ray crystallographic analyses of Thermus thermophilus backtracked RNA polymerase

DNA-dependent RNA polymerase (RNAP) synthesizes RNA complementary to the template DNA. During transcript elongation, RNAP often undergoes backward translocation (‘backtracking’) by dissociating the 3′ end of the nascent RNA transcript from the template DNA. While the backtracked state of RNAP is ina...

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Detalhes bibliográficos
Main Authors: Murayama, Yuko, Sekine, Shun-ichi, Yokoyama, Shigeyuki
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3564623/
https://ncbi.nlm.nih.gov/pubmed/23385762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309113000055
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