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Regulation of transcriptional silencing and chromodomain protein localization at centromeric heterochromatin by histone H3 tyrosine 41 phosphorylation in fission yeast

Heterochromatin silencing is critical for genomic integrity and cell survival. It is orchestrated by chromodomain (CD)-containing proteins that bind to methylated histone H3 lysine 9 (H3K9me), a hallmark of heterochromatin. Here, we show that phosphorylation of tyrosine 41 (H3Y41p)—a novel histone H...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Ren, Bingbing, Tan, Hwei Ling, Nguyen, Thi Thuy Trang, Sayed, Ahmed Mahmoud Mohammed, Li, Ying, Mok, Yu-Keung, Yang, Henry, Chen, Ee Sin
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5758876/
https://ncbi.nlm.nih.gov/pubmed/29136238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx1010
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