Regulation of transcriptional silencing and chromodomain protein localization at centromeric heterochromatin by histone H3 tyrosine 41 phosphorylation in fission yeast

Heterochromatin silencing is critical for genomic integrity and cell survival. It is orchestrated by chromodomain (CD)-containing proteins that bind to methylated histone H3 lysine 9 (H3K9me), a hallmark of heterochromatin. Here, we show that phosphorylation of tyrosine 41 (H3Y41p)—a novel histone H...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Ren, Bingbing, Tan, Hwei Ling, Nguyen, Thi Thuy Trang, Sayed, Ahmed Mahmoud Mohammed, Li, Ying, Mok, Yu-Keung, Yang, Henry, Chen, Ee Sin
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2018
Témata:
Gene regulation, Chromatin and Epigenetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5758876/
https://ncbi.nlm.nih.gov/pubmed/29136238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx1010
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