Blockade of soluble epoxide hydrolase attenuates post-ischemic neuronal hyperexcitation and confers resilience against stroke with TrkB activation

Inhibition and deletion of soluble epoxide hydrolase (sEH) has been suggested to ameliorate infarction in experimental ischemic stroke possibly via vasoactive epoxyeicosatrienoic acids. However, it is unknown whether the neuroprotective mechanisms involve alteration of post-ischemic neuronal transmi...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Chang, Li-Hsin, Lin, Hui-Ching, Huang, Shiang-Suo, Chen, I-Chih, Chu, Kai-Wen, Chih, Chun-Lien, Liang, Yao-Wen, Lee, Yi-Chung, Chen, You-Yin, Lee, Yi-Hsuan, Lee, I-Hui
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5758800/
https://ncbi.nlm.nih.gov/pubmed/29311641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-18558-6
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