Soluble epoxide hydrolase inhibitor enhances synaptic neurotransmission and plasticity in mouse prefrontal cortex

BACKGROUND: The soluble epoxide hydrolase (sEH) is an important enzyme chiefly involved in the metabolism of fatty acid signaling molecules termed epoxyeicosatrienoic acids (EETs). sEH inhibition (sEHI) has proven to be protective against experimental cerebral ischemia, and it is emerging as a thera...

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Vydáno v:J Biomed Sci
Hlavní autoři: Wu, Han-Fang, Yen, Hsin-Ju, Huang, Chi-Chen, Lee, Yi-Chao, Wu, Su-Zhen, Lee, Tzong-Shyuan, Lin, Hui-Ching
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618874/
https://ncbi.nlm.nih.gov/pubmed/26494028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-015-0202-7
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