Soluble epoxide hydrolase inhibitor enhances synaptic neurotransmission and plasticity in mouse prefrontal cortex

BACKGROUND: The soluble epoxide hydrolase (sEH) is an important enzyme chiefly involved in the metabolism of fatty acid signaling molecules termed epoxyeicosatrienoic acids (EETs). sEH inhibition (sEHI) has proven to be protective against experimental cerebral ischemia, and it is emerging as a thera...

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Detalhes bibliográficos
Publicado no:J Biomed Sci
Main Authors: Wu, Han-Fang, Yen, Hsin-Ju, Huang, Chi-Chen, Lee, Yi-Chao, Wu, Su-Zhen, Lee, Tzong-Shyuan, Lin, Hui-Ching
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618874/
https://ncbi.nlm.nih.gov/pubmed/26494028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-015-0202-7
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